IA-2 Ab ELISA

Enzyme immunoassay for the determination of IA-2 autoantibodies in human serum.

INTENDED USE:The RSR IA-2 autoantibody (IA-2 Ab) ELISA Version 2 kit is intended for use by professional persons only, for the quantitative determination of IA-2 Ab in human serum.

GENERAL INFORMATION: Autoantibodies to pancreatic beta cell antigens are important serological markers of type 1 diabetes mellitus (type 1 DM). The antigens recognised by these antibodies include insulin, glutamic acid decarboxylase (GAD65 kDa isoform), the islet cell antigen IA-2 or ICA-512 and zinc transporter 8 (ZnT8).

KIT CHARACTERISTICS:
- Method: ELISA
- Tests: 96
- Incubation Time / Conditions: 16-20 h, 1 h (2-8 °C), 20 min (RT/shaker), 20 min (RT/dark)
- Standard Range: 7.5 - 4,000 U/ml
- Sensitivity analytical: 1.25 U/ml
- Final Sample Volume: 50 µl
- Sample Type: serum
- Isotope / Substrate: TMB 450 nm
- Internal Controls: 2
- Regulatory Status: CE