Mouse CCL8 / MCP-2 Assay Kit

Background:Chemokine (C-C motif) ligand8/Monocyte chemoattractant protein-2 (CCL8/MCP-2) consists of 97 amino acids and is constitutionally-classified as C-C subfamily. CCL8/MCP-2 is produced by monocytes, fibroblasts and epithelial cells, and it shows chemotactic activity to CD4+ T cells, CD8+ T cells, monosytes and NK cells. Though the biological activity of CCL8/MCP-2 in mice is still unknown, it is recently reported that CCL8/MCP-2 in plasma increases with incidence of GVHD (Graft-Versus-Host-Disease) which is a complication of bone-marrow transplantation and the study suggests that CCL8/MCP-2 is associated with immune response within a living organism of mouse.

Description:
This kit is a solid phase sandwich ELISA using 2 kinds of high specific antibodies. Tetra Methyl Benzidine (TMB) is used as a coloring agent (Chromogen). The strength of coloring is proportional to the quantities of Mouse CCL8/MCP-2.

Product features:
The kit contains reagents for 96 determinations;
Microtiter plate consisting of 12x8;
Microtiter plate reader at 450 nm;
Analytical sensitivity: 50 pg/mL