Real Time PCR Detection Kit Treponema pallidum

The Real Time PCR detection Kit Treponema pallidum comprises a series of specific targeted reagents designed for Treponema pallidum detection by using qPCR.

GENERAL INFORMATION:Treponema pallidum is a spirochaete bacterium belonging to the Spirochaetaceae family. Three subspecies of T. pallidum are known: T. pallidum subsp. pallidum, which causes syphilis; T. pallidum subsp. endemicum, which causes bejel or endemic syphilis and T. pallidum subsp. pertenue, which causes yaws. T. pallidum subsp. pallidum is a motile spirochaete that is generally acquired by close sexual contact. The organism can also be transmitted to a fetus by transplacental passage during the later stages of pregnancy, giving rise to congenital syphilis. The organism enters through the skin and the initial lessions are on genitals. In more severe cases, it may gain access to the host by infecting the skeletal bones and central nervous system. Infection with other T. pallidum subspecies (pertenue and endemicum) is acquired through contact with infected skin and are not considered sexually transmitted. These may result in a simple rash but may progress and cause disfiguring skin lesions.

KIT CHARACTERISTICS:
- Assay Mix Target composed by singleplex mixtures of specific forward/reverse primers and probe.
- Resuspension buffer
- DNase/RNase free water
- (OPTIONAL) Internal Control Assay Mix
- Mastermix solution
- Positive control